| manuchandel | Date: Thursday, 10-February-2022, 1:31 PM | Message # 1 |
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| Researchers reveal largest catalog of gene activators
by University of Toronto
Credit: CC0 Public Domain
University of Toronto researchers have created a first-in-class functional catalog of proteins that activate gene expression, with implications for tailored therapy for cancer and other diseases that occur when wrong genes are switched on.
Also known as transcriptional activators for their ability to induce transcription of genes into RNA messages, these proteins are essential for the cells to function properly. Yet little is known about these proteins, and it wasn't clear how many activators there might be in human cells—until now.
The research was led by Mikko Taipale, an associate professor of molecular genetics in the Donnelly Centre for Cellular and Biomolecular Research at the Temerty Faculty of Medicine, in collaboration with Anne-Claude Gingras, a senior investigator at the Lunenfeld-Tanenbaum Research Institute, Sinai Health System and professor of molecular genetics at U of T.
Read more/full article/source - https://phys.org/news/2022-02-reveal-largest-gene.html
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